ODCs

Click node...

2 OMIM references -
2 associated genes
18 signs/symptoms

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
No signs/symptoms info

Porphyria cutanea tarda

Diaphyseal medullary stenosis - bone malignancy

HFE	(UniProt - OMIM)		MTAP	(UniProt - OMIM)
UROD	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	UROD	(0.63)	MTAP

Citations in the biomedical literature:

Porphyria cutanea tarda		Diaphyseal medullary stenosis - bone malignancy
	Synonym(s): - PCT		Synonym(s): - Bone dysplasia - medullary fibrosarcoma - Diaphyseal medullary stenosis - malignant fibrous histiocytoma - Hardcastle syndrome

	Classification (Orphanet): - Inborn errors of metabolism - Rare eye disease - Rare genetic disease - Rare renal disease - Rare skin disease		Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease - Rare oncologic disease

	Classification (ICD10): - Endocrine, nutritional and metabolic diseases -		Classification (ICD10): - Diseases of the musculoskeletal system and connective tissue -

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: adulthood Average age of death: normal Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: - Average age onset: - Average age of death: - Type of inheritance: autosomal dominant

	External references: 2 OMIM references - 1 MeSH reference: D017119		External references: 1 OMIM reference - 1 MeSH reference: C536169

Porphyria cutanea tarda
	Very frequent - Autosomal dominant inheritance - Cutaneous rash - Erythema / erythematous lesions / erythroderma / polymorphous erythema - Irregular / in bands / reticular skin hyperpigmentation - Irregular / patchy skin hypopigmentation - Skin photosensitivity - Thin skin - Vesicles / bullous / exsudative lesions / bullous / cutaneous / mucosal detachment Occasional - Abnormal scarring / cheloids / hypertrophic scars - Acute palsy - Cirrhosis - Collapse / sudden death / cardiac arrest / cardiorespiratory arrest - Cutaneous edema - Hepatic / liver neoplasm / tumor / carcinoma / cancer - Hirsutism / hypertrichosis / Increased body hair - Liver / hepatic steatosis - Obnubilation / coma / lethargia / desorientation - Storage liver disease
Diaphyseal medullary stenosis - bone malignancy
(no data available)